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Organ preservation market: key players, and regional analysis

The practice of keeping healthy organs removed from donors’ bodies is known as organ preservation. The procedure entails removing the donor’s organs, transporting them in storage, and then safely transplanting them into the recipient’s body. It uses various procedures, including hypothermic machine perfusion, static cold storage (SCS), and normothermic machine perfusion (NMP), to keep the kidneys, liver, lungs, heart, and other organs at a constant temperature and oxygen saturation level.

The market for organ preservation in 2021 was worth USD 206.89 million, and by 2030 it will be worth USD 377.97 million, growing at a 6.93% CAGR during the forecast period.

The demand for organ preservation is driven by the rising elderly population in the world and the occurrence of multi-organ failure. Additionally, the market will develop due to increasing initiatives by various governmental and non-governmental organizations to promote organ donation.

Market Dynamics

Drivers

Major drivers propelling the market’s expansion are the rising prevalence of chronic diseases and the global geriatric population. The need for organ preservation operations is rising due to the frequent organ failures caused by serious medical illnesses like diabetes, obesity, cardiovascular disorders (CVDs), and others. The development of novel and cutting-edge methods for organ preservation, such as NMP, is stimulating growth. Additionally, the market growth is being positively impacted by an increase in government and non-government laws and initiatives to promote organ donation. Additional factors, such as increased research and development (R&D) and considerable improvements in the infrastructure for organ preservation, will also significantly impact market growth.

Restraints

The expensive cost of organ transplantation, the large annual disparity between the number of donated and needed organs, and the relatively low level of medical reimbursements for organ donation and transplantation will impede the market’s growth.

Opportunity 

The market for organ preservation systems may rise as a result of rising government investments in healthcare. For instance, according to CMS, the national healthcare spending in the United States increased by 9.7% to USD 4.1 trillion in 2020, or USD 12,500 on average per person, while according to CIHI, the total healthcare spending in Canada will exceed CAD 308 billion in 2021 or CAD 8019 per person. The improved healthcare services will attract more patients and donations, which could accelerate market expansion.

Market Segmentation

By Solution

On the basis of the solution, the market is segmented into perfadex, custodial HTK, the University of Wisconsin, and others.

The University of Wisconsin (UW) solution segment had the largest market share of 48.08%. It is one of the first intracellular organ preservation media. Its increase is due to the availability of metabolically inert substrates like raffinose and lactobionate, which promote better organ transport outcomes and improved physiological performance. The University of Wisconsin solution is perfect for flushing and cold storage of the donor’s liver, kidney, and pancreas since it contains 35.83 g/l of lactobionic acid and 17.83 g/l of raffinose pentahydrate.

By Organ Type

On the basis of organ type, the organ preservation market is segmented into lungs, heart, liver, kidneys, and others.

The kidney segment is the largest market contributor, with a significant revenue share. Renal failure cases and kidney transplant procedures are the key factors influencing the market growth. According to a 2019 estimate from the NHS, around 37.00 million Americans have chronic kidney disease, and nearly 726,000 get the end-stage renal disease each year. Additionally, it is anticipated that several awareness programs highlighting the benefits of kidney transplantation will spur market expansion. For instance, the NHS launched the “Advancing American Kidney Health” Initiative to enhance the quality of life for Americans with renal disease.

By Preservation Technique

On the basis of preservation technique, the organ preservation market is segment into hypothermic machine perfusion, static cold storage, and normothermic machine perfusion.

The normothermic machine perfusion technique is the major market holder with a significant revenue share. Normothermic perfusion mimics the physiologic environment by maintaining the average organ temperature constant while supplying essential substrates for cellular metabolism, oxygenation, and feeding. It is intend to increase the organ’s effectiveness and safety while repairing it in preparation for the transplant.

By End-Use

On the basis of end-user, the market is segment into hospitals, organ transplant centers, and specialty clinics.

The organ transplant centers segment was the largest market contributor in 2022. The largest share of this market segment is due to the rising number of transplant facilities globally.

Regional Analysis 

North America led the entire market with the largest revenue share. This is due to the growing demand and uptake of organ transplantation due to the rise in chronic diseases, such as end-stage diseases. Another significant element influencing North America’s sizable share of the organ preservation market is the region’s need for preservation technologies to maintain organ viability in ex-vivo situations. Additionally, the regional market will expand with the rising number of organ transplantation procedures and the geriatric population.

Key Players 

  • Essential Pharmaceuticals, LLC
  • TransMedics
  • Paragonix Technologies
  • Shanghai Genext Medical Technology
  • Franz Köhler Chemie GmbH
  • Bridge To Life Limited
  • XVIVO Perfusion AB
  • 21st Century Medicine
  • Waters Medical Systems
  • OrganOx Limited
  • Preservation Solutions
  • Transplant Biomedicals
  • Carnamedica
  • Biochefa
  • TX Innovations
  • Institut Georges Lopez
  • Avionord
  • Global Transplant Solutions
  • Organ Preservation Solutions
  • EBERS

The market for organ preservation in 2021 was worth USD 206.89 million, and by 2030 it will be worth USD 377.97 million, growing at a 6.93% CAGR during the forecast period. The demand is increasing due to rising organ failure rates globally, campaigns to promote organ donation. An aging population, and the presence of important actors in both developing and wealthy nations.

The rising number of organ transplantation methods across. The globe and rising instances of various organ disappointment are the central point moving the market development. As per a report distributed by the Wellbeing Assets and Administrations Organization in 2019. Around 36,528 organ transplantation were acted in the U.S. in 2018. And around 95.00% of grown-ups in the nation support organ gift. It additionally detailed that around 17,553 benefactors were kept in 2018 of which 10,722 were expired givers and 6,831 were living contributors.

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